abstract：BACKGROUND:This multicenter, randomized, double-blind, double-dummy, placebo-controlled trial primarily evaluated the efficacy of tadalafil once-daily (OaD) or on-demand ("pro-re-nata"; PRN) treatment, started early post-nsRP. Secondary outcome-measures on quality-of-life (QoL) and treatment satisfaction are reported. ...

journal_title：BMC urology

authors： Patel HR,Ilo D,Shah N,Cuzin B,Chadwick D,Andrianne R,Henneges C,Barry J,Hell-Momeni K,Branicka J,Büttner H

更新日期：2015-04-12 00:00:00

abstract：BACKGROUND:This study describes and compares health-related quality of life (HRQOL) of prostate cancer patients who received either radical prostatectomy (nerve-sparing, nsRP, or non-nerve-sparing, nnsRP) or radiotherapy (external RT, brachytherapy, or both combined) for treatment of localised prostate cancer. METHODS...

journal_title：BMC urology

authors： Eisemann N,Nolte S,Schnoor M,Katalinic A,Rohde V,Waldmann A

更新日期：2015-04-10 00:00:00

abstract：BACKGROUND:Although there is growing evidence of relationship between obesity and some specific stone compositions, results were inconsistent. Due to a greater relationship between metabolic syndrome and some specific stone type, obesity measured by body mass index (BMI) has limitation in determining relationship betwe...

journal_title：BMC urology

authors： Kim JH,Doo SW,Cho KS,Yang WJ,Song YS,Hwang J,Hong SS,Kwon SS

更新日期：2015-03-14 00:00:00

abstract：BACKGROUND:Partial segmental thrombosis of the corpus cavernosum (PSTCC) is a rare disease predominantly occurring in young men. Cardinal symptoms are pain and perineal swelling. Although several risk factors are described in the literature, the exact etiology of penile thrombosis remains unclear in most cases. MRI or ...

journal_title：BMC urology

authors： Sauer S,Goltz JP,Gassenmaier T,Kunz AS,Bley TA,Klein D,Petritsch B

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Cystic renal cell carcinoma (CRCC) is relatively rare; CRCC is frequently misdiagnosed as a benign renal cyst. CRCC carries an excellent prognosis following surgical treatment. The aim of our study was to summarize the management of CRCC and to characterize the prognosis of affected patients. METHODS:A retr...

journal_title：BMC urology

authors： Chen S,Jin B,Xu L,Fu G,Meng H,Liu B,Li J,Xia D

更新日期：2014-11-07 00:00:00

abstract：BACKGROUND:The objective of this population-based study was to assess patient, physician and tumour determinants associated with positive surgical margins after prostatectomy, and to assess the effects of positive surgical margins on prostate cancer-specific survival. METHODS:We included 1'254 prostate cancer patients...

journal_title：BMC urology

authors： Retèl VP,Bouchardy C,Usel M,Neyroud-Caspar I,Schmidlin F,Wirth G,Iselin C,Miralbell R,Rapiti E

更新日期：2014-11-05 00:00:00

abstract：BACKGROUND:Radical prostatectomy (RP) is a common treatment for prostate cancer (PCa). Morbidity, mortality and pathological outcomes may be superior in academic institutions. One explanation may be the involvement of oncology fellowship trained urologists within academic institutions. The literature examining patholog...

journal_title：BMC urology

authors： Nayak JG,Drachenberg DE,Mau E,Suderman D,Bucher O,Lambert P,Quon H

更新日期：2014-10-23 00:00:00

abstract：BACKGROUND:It is well recognized that the presence of positive surgical margins (PSM) after radical prostatectomy (RP) adversely affects cancer specific outcomes and recent evidence from randomized trials supports the use of adjuvant radiotherapy in these cases. However, not all of the patients with PSM develop disease...

journal_title：BMC urology

authors： Vesely S,Jarolim L,Duskova K,Schmidt M,Dusek P,Babjuk M

更新日期：2014-10-02 00:00:00

abstract：BACKGROUND:The purpose of this study was to explore the budget impact of dutasteride plus tamsulosin fixed-dose combination (DUT + TAM FDC) versus tamsulosin monotherapy, in the treatment of patients with benign prostatic hyperplasia (BPH) from the perspective of the Greek healthcare insurance system. METHODS:A Micros...

journal_title：BMC urology

authors： Geitona M,Karabela P,Katsoulis IA,Kousoulakou H,Lyberopoulou E,Bitros E,Xaplanteris L,Papanicolaou S

更新日期：2014-09-26 00:00:00

abstract：BACKGROUND:To review the possible mechanisms proposed to explain the etiology of 46, XX sex reversal by investigating the clinical characteristics and their relationships with chromosomal karyotype and the SRY(sex-determining region Y)gene. METHODS:Five untreated 46, XX patients with SRY-positive were referred for inf...

journal_title：BMC urology

authors： Wu QY,Li N,Li WW,Li TF,Zhang C,Cui YX,Xia XY,Zhai JS

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:The control of the lower urinary tract is a complex, multilevel process involving both the peripheral and central nervous system. Due to lesions of the neuraxis, most spinal cord injury patients suffer from neurogenic lower urinary tract dysfunction, which may jeopardise upper urinary tract function and has ...

journal_title：BMC urology

authors： Leitner L,Walter M,Freund P,Mehnert U,Michels L,Kollias S,Kessler TM

更新日期：2014-08-18 00:00:00

abstract：BACKGROUND:Increasing evidences have documented that microRNAs (miRNAs) act as oncogenes or tumor suppressors in a variety types of cancer. The discovery of tumor associated miRNAs in serum of patients gives rise to extensive investigation of circulating miRNAs in many human cancers which support the use of plasma/seru...

journal_title：BMC urology

authors： Feng Y,Kang Y,He Y,Liu J,Liang B,Yang P,Yu Z

更新日期：2014-06-23 00:00:00

abstract：BACKGROUND:This very large population-based study investigated outcomes after a diagnosis of prostate cancer (PCa) in terms of mortality rates, treatments and adverse effects. METHODS:Among the 11 million men aged 40 years and over covered by the general national health insurance scheme, those with newly managed PCa i...

journal_title：BMC urology

authors： Tuppin P,Samson S,Fagot-Campagna A,Lukacs B,Alla F,CNAMTS scientific board members.,Paccaud F,Thalabard JC,Vicaut E,Vidaud M,Millat B

更新日期：2014-06-13 00:00:00

abstract：BACKGROUND:Renal artery aneurysm is a rare disorder with a high mortality rate in the event of rupture, the most frequent complication, which can also occur in lesions smaller than those indicated for treatment by current criteria. Surgery is still the first-line treatment, although a growing trend toward endovascular ...

journal_title：BMC urology

authors： Rossi M,Varano GM,Orgera G,Rebonato A,Laurino F,De Nunzio C

更新日期：2014-05-28 00:00:00

abstract：BACKGROUND:In patients with neurogenic bladder (NB), elevated intravesical pressures can be transmitted to the upper urinary tract, causing hydronephrosis (HN) and ureteral dilation (UD), which are referred to as upper urinary tract dilation (UUTD). Ureteral obstruction at the bladder wall is another cause for UUTD, bu...

journal_title：BMC urology

authors： Liao L,Zhang F,Chen G

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:Anterior urethral stricture remains a great challenge. We reported our clinical technique and results by using inlay dorsal buccal mucosal graft urethroplasty for repair of anterior urethral stricture. METHODS:From January 2005 to July 2008, 87 male patients (range from 9 to 72 years old) with anterior uret...

journal_title：BMC urology

authors： Liu Y,Zhuang L,Ye W,Ping P,Wu M

更新日期：2014-05-08 00:00:00

abstract：BACKGROUND:Schwannomas are tumours arising from Schwann cells, which sheath the peripheral nerves. Here, we report a rare case of left intrascrotal, extratesticular schwannoma. Although rare, scrotal localisation of schwannomas has been reported in male children, adult men, and elderly men. They are usually asymptomati...

journal_title：BMC urology

authors： Palleschi G,Carbone A,Cacciotti J,Manfredonia G,Porta N,Fuschi A,de Nunzio C,Petrozza V,Pastore AL

更新日期：2014-04-28 00:00:00

abstract：BACKGROUND:CXCL12/CXCR4 transactivation of epidermal growth factor family receptors in lipid raft membrane microdomains on cell surface is thought to mediate tumor growth and subsequent development of metastatic disease. CTCE-9908 is a known inhibitor of CXCR4. Herein, we tested the efficacy of CTCE-9908 in inhibiting ...

journal_title：BMC urology

authors： Wong D,Kandagatla P,Korz W,Chinni SR

更新日期：2014-01-28 00:00:00

abstract：BACKGROUND:The core question of the study was whether adequately achieved HD affected the sexual dysfunction in women on hemodialysis (HD) with chronic renal failure (CRF). METHODS:Thirty-seven female patients on HD, including 18 women with adequate HD and 19 women with non-adequate HD, and 36 healthy controls were in...

journal_title：BMC urology

authors： Kim JH,Doo SW,Yang WJ,Kwon SH,Song ES,Lee HJ,Lim IS,Hwang H,Song YS

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:We evaluated the clinical outcome of low grade Ta bladder cancer followed-up for a long period using the 2004 WHO grading system. METHODS:We retrospectively reviewed 190 patients with primary, low grade Ta bladder cancer. We defined worsening progression (WP) as confirmed high grade Ta, all T1 or Tis/concom...

journal_title：BMC urology

authors： Kobayashi H,Kikuchi E,Mikami S,Maeda T,Tanaka N,Miyajima A,Nakagawa K,Oya M

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:European treatment guidelines recommend the use of hormonal therapy for the treatment of advanced prostate cancer, including castration-resistant prostate cancer (CRPC), but there is little understanding of how common practices in prostate cancer treatment compare across Europe. The aim of this analysis was ...

journal_title：BMC urology

authors： Sternberg CN,Baskin-Bey ES,Watson M,Worsfold A,Rider A,Tombal B

更新日期：2013-11-09 00:00:00

abstract：BACKGROUND:Sacral neuromodulation operations have usually been performed based on 2D fluoro images. However, sacral nerve stimulation lead implantation may be challenging when the normal anatomy is confused by obesity or congenital anomalies. Thus the surgical navigation and intraoperative imaging methods could be help...

journal_title：BMC urology

authors： Hellström PA,Katisko J,Finnilä P,Vaarala MH

更新日期：2013-10-16 00:00:00

abstract：BACKGROUND:Pheochromocytoma (paraganglioma) of the urinary bladder is a rare tumor. Herein we sought to review the contemporary literature on pheochromocytomas of the urinary bladder in order to further illustrate the presentation, treatment options and outcomes of patients diagnosed with these tumors. METHODS:A compr...

journal_title：BMC urology

authors： Beilan JA,Lawton A,Hajdenberg J,Rosser CJ

更新日期：2013-04-29 00:00:00

abstract：BACKGROUND:The objective of this study is to determine in a case series (four patients) how calcified deposits in renal papillae are associated with the development of calcium oxalate monohydrate (COM) papillary calculi. METHODS:From the recently collected papillary calculi, we evaluated retrospectively patients, subj...

journal_title：BMC urology

authors： Grases F,Costa-Bauzá A,Prieto RM,Conte A,Servera A

更新日期：2013-03-11 00:00:00

abstract：:This review summarizes recent literature on advances regarding renal and ureteral calculi, with particular focus in areas of recent advances in the overall field of urolithiasis. Clinical management in everyday practice requires a complete understanding of the issues regarding metabolic evaluation and subgrouping of s...

journal_title：BMC urology

authors： Rosa M,Usai P,Miano R,Kim FJ,Finazzi Agrò E,Bove P,Micali S,International Translational Research in Uro-Sciences Team (ITRUST).

更新日期：2013-02-16 00:00:00

abstract：BACKGROUND:To explore the additive effect of urinary incontinence, in people with comorbid depression, on health related quality of life. METHODS:Males and females, 15 to 95 years (n = 3010, response rate 70.2%) were interviewed face to face in the 1998 Autumn South Australian Health Omnibus Survey. RESULTS:Self-repo...

journal_title：BMC urology

authors： Avery JC,Stocks NP,Duggan P,Braunack-Mayer AJ,Taylor AW,Goldney RD,MacLennan AH

更新日期：2013-02-16 00:00:00

abstract：BACKGROUND:Previous studies report association of contraceptives with moderate increase in urinary tract infection among sexually active premenopausal women. The aim of our study was to find out whether the use of hormonal contraceptives has any effect on microbiota of the vagina in the contraceptives users in Khairpur...

journal_title：BMC urology

authors： Kazi YF,Saleem S,Kazi N

更新日期：2012-08-18 00:00:00

abstract：BACKGROUND:Upper urinary tract cancer is typically diagnosed with urine cytology and imaging techniques. These assays can be limited by sensitivity, specificity, or technical issues making some diagnoses difficult. CASE PRESENTATION:A 73-year old man presented to the clinic with a right renal pelvis filling defect tha...

journal_title：BMC urology

authors： Silverberg DM

更新日期：2012-08-08 00:00:00

abstract：BACKGROUND:PSA-directed prostate cancer screening leads to a high rate of false positive identifications and an unnecessary biopsy burden. Epigenetic biomarkers have proven useful, exhibiting frequent and abundant inactivation of tumor suppressor genes through such mechanisms. An epigenetic, multiplex PCR test for pros...

journal_title：BMC urology

authors： Van Neste L,Bigley J,Toll A,Otto G,Clark J,Delrée P,Van Criekinge W,Epstein JI

更新日期：2012-06-06 00:00:00

abstract：BACKGROUND:Renal cell carcinoma can cause various paraneoplastic syndromes including metabolic and hematologic disturbances. Paraneoplastic hypereosinophilia has been reported in a variety of hematologic and solid tumors. We present the first case in the literature of severe paraneoplastic hypereosinophilia in a patien...

journal_title：BMC urology

authors： Todenhöfer T,Wirths S,von Weyhern CH,Heckl S,Horger M,Hennenlotter J,Stenzl A,Kanz L,Schwentner C

更新日期：2012-03-21 00:00:00

abstract：BACKGROUND:The aim was to retrospectively assess the results of treatment of upper urinary tract stones with the Sonolith vision manufactured by EDAP, and purchased in 2004. METHODS:The subjects were 226 Japanese patients who underwent extracorporeal shock wave lithotripsy (ESWL) alone as an initial treatment and coul...

journal_title：BMC urology

authors： Nakamura K,Tobiume M,Narushima M,Yoshizawa T,Nishikawa G,Kato Y,Katsuda R,Zennami K,Aoki S,Yamada Y,Honda N,Sumitomo M

更新日期：2011-12-12 00:00:00

abstract：BACKGROUND:Obstetric fistula although virtually eliminated in high income countries, still remains a prevalent and debilitating condition in many parts of the developing world. It occurs in areas where access to care at childbirth is limited, or of poor quality and where few hospitals offer the necessary corrective sur...

journal_title：BMC urology

authors： Kayondo M,Wasswa S,Kabakyenga J,Mukiibi N,Senkungu J,Stenson A,Mukasa P

更新日期：2011-12-07 00:00:00

abstract：BACKGROUND:Caveolae play a significant role in disease phenotypes such as cancer, diabetes, bladder dysfunction, and muscular dystrophy. The aim of this study was to elucidate the caveolin-1 (CAV1) protein expression in renal cell cancer (RCC) and to determine its potential prognostic relevance. METHODS:289 clear cell...

journal_title：BMC urology

authors： Steffens S,Schrader AJ,Blasig H,Vetter G,Eggers H,Tränkenschuh W,Kuczyk MA,Serth J

更新日期：2011-12-07 00:00:00

abstract：BACKGROUND:Survival rate for patients presenting muscle invasive bladder cancer is very low, and useful therapeutic target has not been identified yet. In the present study, new COX2 downstream signals involved in urothelial carcinoma cell survival were investigated in vitro and in vivo. METHODS:COX2 gene was silenced...

journal_title：BMC urology

authors： Shimada K,Anai S,Marco DA,Fujimoto K,Konishi N

更新日期：2011-05-18 00:00:00

abstract：BACKGROUND:To examine the expression of type 1 plasminogen inhibitor (PAI-1) in clear cell renal cell carcinoma (CCRCC), and its possible association with microvessel density (MVD), the expression of thrombospondin-1 (TSP-1), nuclear grade, tumour stage, continuously coded tumour size (CCTS) and to assess the value of ...

journal_title：BMC urology

authors： Zubac DP,Wentzel-Larsen T,Seidal T,Bostad L

更新日期：2010-12-03 00:00:00

abstract：BACKGROUND:Laparoscopic single-site surgery has recently emerged in the field of urology and this minimally-invasive surgery has resulted in a further reduction in morbidity compared with traditional laparoscopy. We present our initial experience with laparoendoscopic single-site surgery of partial adrenalectomy (LESS-...

journal_title：BMC urology

authors： Yuge K,Miyajima A,Hasegawa M,Miyazaki Y,Maeda T,Takeda T,Takeda A,Miyashita K,Kurihara I,Shibata H,Kikuchi E,Oya M

更新日期：2010-11-23 00:00:00

abstract：BACKGROUND:Fesoterodine is an antimuscarinic for the treatment of overactive bladder, a syndrome of urgency, with or without urgency urinary incontinence (UUI), usually with increased daytime frequency and nocturia. Our objective was to develop predictive models to describe the dose response of fesoterodine. METHODS:D...

journal_title：BMC urology

authors： Cardozo L,Khullar V,El-Tahtawy A,Guan Z,Malhotra B,Staskin D

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the characteristics of prostate cancer patients who were diagnosed at repeat biopsy and compare them to non-cancerous patients or patients who were diagnosed at initial biopsy. METHODS:We carried out a retrospective analysis of clinical and pathological data from 576...

journal_title：BMC urology

authors： Yuasa T,Tsuchiya N,Kumazawa T,Inoue T,Narita S,Saito M,Horikawa Y,Satoh S,Habuchi T

更新日期：2008-11-10 00:00:00

abstract：BACKGROUND:The indications for nephron-sparing surgery are expanding constantly. One major contributing fact for this development is the improvement of haemostatic techniques following excision of the tumor. Nevertheless, postoperative bleeding complications still occur. To prevent this, we prospectively studied the ef...

journal_title：BMC urology

authors： Simon J,de Petriconi R,Meilinger M,Hautmann RE,Bartsch G Jr

更新日期：2008-04-29 00:00:00

abstract：BACKGROUND:To investigate the factor structure, dimensionality and construct validity of the (5-item) PRAFAB questionnaire score in women with stress urinary incontinence (stress UI). METHODS:A cross validation study design was used in a cohort of 279 patients who were randomly divided into Sample A or B. Sample A was...

journal_title：BMC urology

authors： Hendriks EJ,Bernards AT,Staal JB,de Vet HC,de Bie RA

更新日期：2008-01-24 00:00:00